Indian Journal of Public Health Research & Development

Punit Chitlangia ¹, Samit Purohit ¹, Chintan Narad ², Rohan Bhise ²

Affiliations
1 Dept. of Medical Oncology, KMIO, IN
2 Dept. of Medical Oncology, Kidwai Memorial Institute of Oncology, (KMIO), Bangalore -29, IN

Abstract

Plasmablastic lymphoma (PBL) is a rare variant of a diffuse B-cell lymphoma that is most commonly found in the oral cavity affecting the mucosa, and so named for its blastoid morphology and immunophenotype. Oral PBL has been treated heterogeneously and well defined treatment guidelines are still lacking. It includes chemotherapy, radiotherapy, combination of both or local excision followed by radiation. Prognosis is usually poor regardless of the site of origin. The clinical course is very aggressive with most of the patients dying in the first year after diagnosis. Here we present a case who was treated with high grade lymphoma protocol, CODOX-M alternating with IVAC followed by radiotherapy&Patient showing a good clinical response.

Keywords

Oral Plasmablastic Lymphoma, HIV-Negative, CODOX-M (Cyclophosphamide O-vinccristine DOX-doxorubicin M-methotrexate), IVAC (I-ifosfamide V-vincristine A-cytosine arabinoside C-cisplatin), LCA(Leucocyte Common Antigen)

Full Text

     

Punit Chitlangia ¹, S. V. Kumaraswamy ², Abhishek Mathur ³

Affiliations
1 Dept. of Oral Oncology, KMIO, IN
2 Dept. of Oral Maxillofacial Surgery, VS Dental College & Hospital, Bangalore, IN
3 NMDC, Delhi, IN

Abstract

Lymhangioma is a benign malformation of the lymphatic channels. The anterior two -third on the dorsal surface of the tongue is the most common site for intra oral lymphangioma leading to macroglossia. We present a case of lymhangiomatous macroglossia in a 25 year old male who underwent surgical excision of the lesion followed by a primary closure. On follow-up after, there was an improved tongue appearance and good tongue function.

Keywords

Lymphangioma, Macroglossia

Full Text